In vitro fertilization treatment has become more common with the rise of the modern era and the associated habits. The IVF procedure can be simply defined in one line but the procedure is highly complex involving a number of tests and analysis. One such test is the PGD. Abbreviated as a preimplantation genetic diagnosis it is one of the most advanced genetic testing methods. It has become of the most invaluable adjunct to the IVF treatment to promote higher success rates of the procedure and healthy pregnancies. Let us take a look at what are PGD and its benefits in IVF.
What is PGD?
The preimplantation genetic diagnosis is a diagnostic procedure that is used to screen for any genetic defects contained within the embryos created during IVF. This procedure is done before the transfer of the embryo into the uterus. The ultimate goal of PGD is to diagnose the presence of any genetic disorders through the examination of DNA and eliminate it. This decreases the chances of the defective genes being passed to the child. The embryos containing defective genes are separated from healthy ones which are transferred into the uterus.
What Does PGD Diagnose?
The process of PGD is highly complex. It requires an embryologist to examine embryos and every gene of the embryo. The process is highly recommended for couples who have a family history of any genetic disease. Though you don’t have the disease, there are chances that you are a carrier of the disease and the passing of the genes to your child may result in the disease.
- The PGD process looks for any abnormalities or translocation in the genetic sequence. The genetic defects lead to miscarriage or birth defects which can be avoided by the diagnosis procedure before IVF.
- The PGD procedure also looks for chromosomal translocations. In this type of translocation, the parts of chromosomes are interchanges or go missing leading to diseases such as Down’s syndrome.
- It also helps to detect single-gene disorders. There are around 4,000 single-gene including Marfan syndrome, Huntington disease, hemophilia, cystic fibrosis, or muscular dystrophy.
- The success of PGD lies in the hands of the doctor and the clinic like the best PGD clinic in Thailand.
Benefit of PGD
The first and foremost benefit of PGD is that it lowers the risk of genetic disorders being passed to the children who are conceived via in vitro fertilization.
- It is used to diagnose more than hundreds of known genetic diseases and disorders
- It allows the carrier parents of genetic diseases to conceive with a significantly reduced risk of passing the disease to their children.
- The PGD technique separates unhealthy embryos from healthy one. Thus it prevents the unhealthy embryos from being transferred to the uterus. This increases the odds of a successful pregnancy through IVF.
- It gives the patients a chance to reassess their decision to continue with the pregnancy in case the embryos are flawed.
- The parents should be ready to face any result that comes after PGD diagnosis.
Who Should Consider PGD?
- The parents who have a history of a genetic disorder can consider this procedure.
- If you have suffered more than one miscarriage or complications then the doctor can perform PGD and find the healthiest embryo for transfer.
It is important to keep in mind that PGD is not a comprehensive test for all possible genetic disorders. Also, it doesn’t entirely eliminate the risk of the child having the disease that was diagnosed. The PGD may also reveal that the entire embryo is genetically flawed. However, most of the patients who are good candidates for IVF outweigh potential problems.
PGD testing is a highly complex test and has to be performed by professional and experienced doctors. Visit the best PGD clinics in Bangkok for a precise PGD to be performed.